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|Product Name:||Prilocaine||CAS No.:||721-50-6|
|Appearence:||white crystalline powder||Standard:||USP|
|Export Market:||Global||Packing Methods:||Special Disguised Package or Customized Guarantee 100% Custom Pass Rate|
|Delivery time:||3-7 working days||Delivery Method:||by express, like EMS, HKEMS, FedEx, TNT, DHL, UPS, Bpost etc|
|Shelf life:||2years||Payment Methods:||Western Union, MoneyGram, T/T, Bitcoin|
Pharmaceutical Grade Local Anaesthetic Drugs Prilocaine 721-50-6 For Pain Killer
Prilocaine Quick Details
|Appearance||White crystalline powder.|
|Solubility||Very soluble in alcohol and in acetone; slightly soluble in water.|
|Shelf Life||36 months|
|Shelf life||2 years|
|Stradge||Store in sealed containers at cool & dry place. Keep away from light, moisture, pest infestation|
|Packing Methods||designed disguised packing ways, 100% pass custom guarantee|
|Delivery time||within 18 hours after payment confirmed|
|Payment||T/T, Western Union,Money Gram , Bitcoin|
|Usage||Prilocaine topical is a local anesthetic (numbing medication).it acts better than procaine, the local anesthetic strength and speed are similar to lidocaine, but acts a longer time|
Prilocaine is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Lö Fgren. In its injectable form (trade name Citanest), it is often used in dentistry.
Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia.
Prilocaine topical is a local anesthetic (numbing medication). It works by blocking nerve signals in your body.
Prilocaine topical is used to numb the skin, or surfaces of the penis or vagina, in preparation for a medical procedure or to lessen the pain of inserting a medical instrument such as a tube or speculum.
Prilocaine Usage And Synthesis:
Prilocaine belongs to amide local anesthetic drug with its anesthesia intensity and speed being similar as lidocaine but with a longer duration period and weaker effect on vasodilation. It has a lower toxicity than lidocaine. It is clinically for local anesthesia, especially suitable for treating patients who are not allowed to use adrenaline.
Its 3% solution has a similar local anesthesia efficacy as the anesthesia drug of 2% lidocaine together with adrenaline. It has a slow onset time which lasts about 6 ~ 7min and the duration time of about 1.5 ~ 2h. It has a strong penetration capability through mucous membranes. Adrenaline has a slightly prolonged duration of action. PPB is 55% and T1/2 of about 1.5h. It is subject to liver metabolism with its metabolites nitroso toluidine being able to oxidize hemoglobin to form methemoglobin. It can be transported to the fetus through the placenta.
once the usage amount exceeds 600mg, methaemoglobinaemia can occur with cyanosis, tachycardia, headache, dizziness and weakness occurring.
patients of anemia, congenital or acquired methaemoglobinaemia, respiratory failure or heart failure and hypoxic patients should be disabled. It is forbidden for applied to obstetric anesthesia.
Prilocaine Usage and dosage:
infiltration anesthesia: 0.5% to 1% solution with the duration of action of 1 to 1.5 hours.
Nerve blocking anesthesia: use 1% to 2% solution with the duration of action being 2-3 hours.
Epidural anesthesia: use10 to 30 mL of 1.5% ~ 1% solution with the duration of action of 2.5 to 3.5 hours. Use a maximum dose of 600 mg.
|Description||Almost white powder||White or almost white powder|
|Solubility||Complies||Very soluble in alcohol and in acetone; Slightly soluble in water.|
|Identification||Complies||By IR comma; To match with the working standard|
|Residue on ignition||0.05percnt;||≤0.1percnt;|
|Related compound A||Not detected||≤0.01%|
|Related compounds||Complies||Not more than 0.2percnt; Of any individual impurity|
|Complies||Not more than one impurity exceeds 0.1percnt;|
|0.13percnt;||Not more than 0.5% of total impurities|
|Residual solvents||Not detected|
|Not detected||Ethanol Not more than0.5%|
|Conclusion; Conforms to USP37|
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6.Delivery Time: US :3-5 days, UK: 4-7 days, Canada: 3-7 days, Europe: 6-10 days
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